Sex-Specific Association of Left Ventricular Function With Mortality in Severe Mitral Regurgitation.

ABSTRACT:

Importance

The association between left ventricular (LV) systolic dysfunction and adverse outcomes in patients with severe degenerative mitral regurgitation (MR) may vary by sex.

Objective

To investigate the sex-specific association of LV systolic function with mortality in patients with severe degenerative MR.

Design, setting, and participants

This retrospective cohort study included consecutive patients who underwent surgery for severe degenerative MR at 2 tertiary hospitals in South Korea from 2006 to 2020. Preoperative LV ejection fraction (LVEF) and LV global longitudinal strain (LV-GLS) were measured, with absolute LV-GLS values reported. Patients were stratified by LVEF (≤55%, >55% to ≤60%, and >60%) and LV-GLS (<19.9%, ≥19.9% to <23.4%, and ≥23.4%) tertiles. M

SUBMITTER: Kwak S 

PROVIDER: S-EPMC11959442 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature