Baseline and changes in prognostic nutritional index associate with heart failure hospitalization and all-cause death in patients with cardiac pacemaker.

ABSTRACT:

Object

The study evaluated prognostic nutritional index (PNI) levels and changes as predictors of heart failure hospitalization (HFH) and mortality in cardiac pacemaker patients.

Methods

PNI was calculated on admission and at the end of the 1-month follow-up, and their net changes (Δ) were calculated by PNI at follow-up minus the corresponding PNI on admission. The optimal cutoff value of baseline PNI was determined by the ROC curve. Based on this optimal cutoff value or the change in PNI during follow-up, patients were divided into high-PNI and low-PNI groups, or into improved PNI group (ΔPNI > 0) and deteriorated group (ΔPNI ≤ 0). The crude and adjusted cox proportional hazard models were used to analyze the associations between adverse events and PNI or ΔPNI. Restricted c

SUBMITTER: Zhang J 

PROVIDER: S-EPMC11959783 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature