The trajectory of depressive symptoms and the association with quality of life and suicidal ideation in patients with major depressive disorder.

ABSTRACT:

Background

Major depressive disorder (MDD) is the most prevalent mental health disorder globally. However, the association between depressive symptom trajectories in the early period and subsequent mental health outcomes remains not fully elucidated. This study aimed to delineate the depressive symptom trajectories during the initial phase of treatment, identify baseline characteristics associated with these trajectories, and explore the association of trajectories with subsequent quality of life and suicidal ideation.

Methods

Participants were from the Depression Cohort in China. The diagnosis of MDD was assessed using the Mini-International Neuropsychiatric Interview (M.I.N.I.). Information on depressive symptom severity, quality of life, suicidal ideation and other demogr

SUBMITTER: Lai W 

PROVIDER: S-EPMC11959785 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature