Factors associated with clinical antimicrobial resistance in China: a nationwide analysis.

ABSTRACT:

Background

Antimicrobial resistance (AMR) represents a critical global health threat, necessitating the identification of factors that contribute to its emergence and proliferation. We used a "One Health" perspective to evaluate the association of human and veterinary antibiotic usage, environmental factors, socio-economic factors, and health care factors with clinical AMR in China.

Methods

We analyzed data from 31 provincial-level administrative divisions in China, encompassing 20,762,383 bacterial isolates sourced from the China Antimicrobial Resistance Surveillance System dataset between 2014 and 2022. A β regression model was used to explore the relationship of AMR with multiple variables. We also estimated the contribution of factors associated with AMR, and evaluated t

SUBMITTER: Zhou W 

PROVIDER: S-EPMC11959846 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature