Characteristics and sex differences in bronchopulmonary dysplasia-related pulmonary hypertension.

ABSTRACT:

Background

Pulmonary hypertension (PH) secondary to bronchopulmonary dysplasia (BPD) is associated with increased mortality. This study aims to elucidate the risk factors for BPD-PH development and the long-term prognostic factors in pediatric BPD.

Methods

We analyzed 1082 BPD patients under the age of three. Univariate and multivariate regression were performed to determine the final model. Risk stratification was performed based on the predicted risk score, and Kaplan-Meier survival curves were used to compare survival rates.

Results

The in-hospital mortality rate of severe BPD was three times than non-severe BPD, and pediatric BPD-PH had twice the mortality compared to BPD without PH. The incidence of BPD was 1.7 times higher in males, but there were no sex-specifi

SUBMITTER: Zhou D 

PROVIDER: S-EPMC11959970 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature