Maternal urinary concentrations of bisphenol A during pregnancy and birth size in children from the Odense Child Cohort.

ABSTRACT:

Background

Bisphenol A (BPA) is widely used in the manufacturing of plastics. BPA can pass the placental barrier and influence fetal development. Due to its estrogenic and anti-androgenic properties, BPA may contribute sex-specific differences in developmental effects. We examined associations between maternal urinary concentrations of BPA and birth size.

Methods

In this cohort study of 832 mother-child pairs from the Odense Child Cohort, pregnant women provided spot urine samples at gestational week 28, which were analyzed for BPA by isotope diluted LC-MS/MS. Osmolality adjusted urinary BPA concentrations were categorized into quartiles. Mother-child characteristics were obtained from hospital records and questionnaires. Linear regression analyses examining the association

SUBMITTER: Beck AL 

PROVIDER: S-EPMC11960018 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature