Exploring the association between the degree of pyuria and urinary tract infections.

ABSTRACT: We aim to define the optimal white cell count threshold that correlates with a clinically significant urinary tract infection, as there is insufficient data exploring this in the adult population. We conducted a retrospective cohort study at the Royal Melbourne Hospital analyzing urine samples collected over 6 months in 2022. Urinary tract infection (UTI) was defined as the presence of symptoms (dysuria, urgency, frequency, flank pain, or loin to groin pain) and isolation of a uropathogen with colony counts greater than 10⁷ CFU/L. The relationship between urinary white cell count, growth of uropathogen, and likelihood of UTI was estimated using locally weighted scatterplot smoothing. Of the 6,328 samples included, at a urinary white cell count of less than 10 per microliter, 38%

SUBMITTER: Tien H 

PROVIDER: S-EPMC11960134 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature