Disrupting the balance: how acne duration impacts skin microbiota assembly processes.

ABSTRACT: Growing interest in the impact of microbial balance on health has driven studies on the ecological processes shaping the skin microbiota. Skin diseases, which alter the skin's local environment, can disrupt the microbial structure and interact with the disease itself. However, research on microbial assembly in diseased skin remains limited. In this study, we applied ecological models to characterize the processes shaping the skin microbiota in acne patients, considering the impact of disease duration on both skin pores and surfaces using bacterial amplicon sequencing. Our results revealed a significant shift in microbial diversity on the skin surface of patients with long-term acne. Further microbial community analyses showed a transition in ecological processes from healthy to diseased sk

SUBMITTER: Sun L 

PROVIDER: S-EPMC11960176 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature