Carbapenem-resistant <i>Morganella morganii</i> carrying <i>bla</i>_KPC-2 or <i>bla</i>_NDM-1 in the clinic: one-decade genomic epidemiology analysis.

ABSTRACT: Carbapenem-resistant Morganella morganii (CRMM) isolates, particularly those producing Klebsiella pneumoniae carbapenemase-2 (KPC-2) or New Delhi metallo-β-lactamase-1 (NDM-1), are increasingly being recognized as causative agents of nosocomial infections. However, systematic phylogeography and genetic characterization of these isolates worldwide are still lacking. Here, through seven years of surveillance of CRMM in a tertiary hospital, we analyzed the genomic characteristics of bla_KPC-2- or bla_NDM-1-positive CRMM isolates. Furthermore, we conducted a global genomic epidemiological study of Morganella spp. harboring bla_KPC or bla_NDM using the NCBI database over the past decade. By combining the timeline

SUBMITTER: Yao J 

PROVIDER: S-EPMC11960177 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature