Early steroid withdrawal and kidney transplant outcomes in first-transplant and retransplant recipients.

ABSTRACT:

Background

Early steroid withdrawal (ESW) is often preferred over conventional steroid maintenance (CSM) therapy for kidney transplant recipients with low immunological risks because it may minimize immunosuppression-related adverse events while achieving similar transplant outcomes. However, the risk-benefit balance of ESW could be less favorable in retransplant recipients given their unique immunological risk profile. We hypothesized that the association of ESW with transplant outcomes would differ between first-transplant and retransplant recipients.

Methods

To assess whether the impact of ESW differs between first and retransplant recipients, we studied 210 086 adult deceased-donor kidney transplant recipients using the Scientific Registry of Transplant Recipients. Recip

SUBMITTER: Bae S 

PROVIDER: S-EPMC11960740 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature