PathoSeq-QC: a decision support bioinformatics workflow for robust genomic surveillance.

ABSTRACT:

Motivation

Recommendations on the use of genomics for pathogens surveillance are evidence that high-throughput genomic sequencing plays a key role to fight global health threats. Coupled with bioinformatics and other data types (e.g., epidemiological information), genomics is used to obtain knowledge on health pathogenic threats and insights on their evolution, to monitor pathogens spread, and to evaluate the effectiveness of countermeasures. From a decision-making policy perspective, it is essential to ensure the entire process's quality before relying on analysis results as evidence. Available workflows usually offer quality assessment tools that are primarily focused on the quality of raw NGS reads but often struggle to keep pace with new technologies and threats, and fail to pr

SUBMITTER: Leoni G 

PROVIDER: S-EPMC11961196 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature