Genome mining reveals the biosynthetic potential of a novel Lysinibacillus zambalensis sp. nov., isolated from a hyperalkaline spring.

ABSTRACT: A novel bacterium, designated as strain M3^T, was isolated from a hyperalkaline spring in the Philippines and identified as a new species within the genus Lysinibacillus through 16 S rRNA gene sequence and genomic analyses. Although strain M3^T shared a high 16 S rRNA gene sequence similarity (> 98.7%) with many Lysinibacillus species, the digital DNA-DNA hybridization and orthologous average nucleotide identity values between strain M3^T and its closet relative, Lysinibacillus xylanilyticus DSM 23,493^T, were 41.2% and 90.6%, respectively-both below the established threshold for prokaryotic species delineation. Genome mining of the 5.3 Mbp-draft genome of strain M3^T revealed eight biosynthetic gene clusters, which shared little sequence s

SUBMITTER: Aja JA 

PROVIDER: S-EPMC11961540 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature