Amplicon-based analysis reveals link between adolescent acne and altered facial skin microbiome induced by negative emotional states.

ABSTRACT:

Introduction

The skin microbiome is integral to maintaining skin homeostasis and is involved in the pathogenesis of acne. Emerging evidence supporting the 'brain-skin axis' suggests that psychological stress may exacerbate acne. Both negative emotional states and acne are highly prevalent among adolescents. Although research has begun to explore this relationship, the role of the skin microbiome in adolescents experiencing emotional disturbances and acne remains poorly understood.

Methods

166 adolescents aged 15-18 were divided into four distinct groups based on their emotional health and acne severity: no acne or negative emotions (NC), acne without negative emotions (NS), negative emotions without acne (YC), and acne with negative emotions (YS). Skin samples were collected

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11961944 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature