Polymorphic transposable elements contribute to variation in recombination landscapes.

ABSTRACT: Meiotic recombination is a prominent force shaping genome evolution, and understanding why recombination rates vary within and between species has remained a central, though challenging, question. Variation in recombination is widely thought to influence the efficacy of selection in purging transposable elements (TEs), prevalent selfish genetic elements, leading to widely observed negative correlations between TE abundance and recombination rates across taxa. However, accumulating evidence suggests that TEs could instead be the cause rather than the consequence of this relationship. To test this prediction, we formally investigated the influence of polymorphic, putatively active TEs on recombination rates. We developed and benchmarked an approach that uses PacBio long-read sequencing to ef

SUBMITTER: Huang Y 

PROVIDER: S-EPMC11962413 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature