The PBAP chromatin remodeling complex mediates summer diapause via H3K4me3-driven juvenile hormone regulation in <i>Colaphellus bowringi</i>.

ABSTRACT: Diapause, a developmental arrest mechanism, helps animals to survive seasonal changes via endocrine regulation. While obligate diapause is genetically programmed, facultative diapause is typically triggered by environmental cues such as photoperiod. In insects, this often leads to reproductive diapause characterized by reduced juvenile hormone (JH) signaling, resulting in ovarian arrest and lipid accumulation. However, the molecular link between photoperiod and hormonal control remains poorly understood. In this study, we investigated the cabbage beetle Colaphellus bowringi as our model system. This species exhibits a photoperiodic response, where short-day (SD) conditions promote reproduction, whereas long-day (LD) conditions induce diapause. Our research identified the PBAP chroma

SUBMITTER: Tian Z 

PROVIDER: S-EPMC11962415 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature