Origin of plasmid-mediated quinolone resistance determinant QnrA.

ABSTRACT: Plasmid-mediated resistance to quinolones is increasingly reported in studies of Enterobacteriaceae. Using a PCR-based strategy, a series of gram-negative species were screened for qnrA-like genes. Shewanella algae, an environmental species from marine and fresh water, was identified as its reservoir. This is a one of the very few examples of progenitor identification of an acquired antibiotic resistance gene.

SUBMITTER: Poirel L 

PROVIDER: S-EPMC1196254 | biostudies-literature | 2005 Aug

REPOSITORIES: biostudies-literature