Invasive Group A Streptococcal Infection in Children, 1992-2023.

ABSTRACT:

Importance

The resurgence of invasive group A streptococcal (iGAS) infections and progress in GAS vaccine development emphasize the importance of understanding current trends in the epidemiology of iGAS.

Objective

To describe the epidemiology of pediatric iGAS over a 32-year period.

Design, setting, and participants

This case series uses population-based surveillance data for iGAS in Toronto and Peel Region, Canada, including emm typing from Canada's National Microbiology Laboratory and population data from Statistics Canada. All children (age <18 years) with iGAS from January 1, 1992, to December 31, 2023, were included. Data were analyzed from July 15, 2023, to September 1, 2024.

Main outcomes and measures

Outcomes of interest were disease incidence over time

SUBMITTER: Dabaja-Younis H 

PROVIDER: S-EPMC11962665 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature