Long-Term Seizure Outcomes in Autoimmune Encephalitis.

ABSTRACT:

Introduction

Seizures are common in autoimmune encephalitis (AE), but identifying patients at risk of chronic epilepsy in the post-acute phase remains challenging. This study aims to identify risk factors of treatment-resistant postencephalitic epilepsy.

Methods

This retrospective cohort study included patients with AE who experienced new-onset seizures within one year of symptom onset from two tertiary care centers in New York. EEG findings were analyzed separately based on whether the EEG recording was obtained in the acute (<3 months from symptom onset) or subacute phase. A multivariate logistic regression model was used to identify independent predictors of postencephalitic epilepsy.

Results

Eighty-nine patients were included (median age: 33 years). Neural antibod

SUBMITTER: Jia L 

PROVIDER: S-EPMC11962926 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature