The impact of multimorbidity on Quality of Life in inflammatory myopathies: A cluster analysis from the COVAD dataset.

ABSTRACT:

Objective

The presence of comorbidities can substantially affect patients' quality of life, but data regarding their impact on idiopathic inflammatory myopathies (IIMs) are limited.

Methods

We examined the prevalence of comorbidities in IIM patients, other autoimmune rheumatic diseases (oAIRDs) and healthy controls (HCs), using data from the self-reported COVAD-2 survey. We defined basic multimorbidity (BM) as the presence of ≥2 non-rheumatic chronic conditions and complex multimorbidity (CM) as the presence of ≥3 non-rheumatic chronic conditions affecting ≥3 organ systems. Hierarchical clustering on principal components was performed for grouping.

Results

Among the COVAD respondents, 1558 IIMs, 4591 oAIRDs and 3652 HCs were analysed. IIMs exhibited a high burden of c

SUBMITTER: Fornaro M 

PROVIDER: S-EPMC11962953 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature