Trends in Global Burden and Socioeconomic Profiles of Atrial Fibrillation and Atrial Flutter: Insights from the Global Burden of Disease Study 2021.

ABSTRACT:

Background

Understanding trends in atrial fibrillation (AF) and atrial flutter (AFL) is crucial for effective prevention. This study quantifies the burden and identifies key risk factors for AF/AFL across 204 countries and territories from 1990 to 2021.

Methods

Using data from the Global Burden of Disease (GBD) study 2021, we employed average annual percentage change (AAPC) and Bayesian Age Period Cohort (BAPC) modelling to assess trends and future projections, with a focus on disparities across Socio-Demographic Index (SDI) levels.

Results

In 2021, AF/AFL remained the most common arrhythmia globally, with a prevalence of 52.55 million, 8.36 million disability-adjusted life years (DALYs), and 0.34 million deaths. For each 0.1 increase in SDI, age-standardized mortalit

SUBMITTER: Tan SCW 

PROVIDER: S-EPMC11963203 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature