Caregiver-child interaction and early childhood development among preschool children in rural China: the possible role of blood epigenome-wide DNA methylation.

ABSTRACT:

Background

While the association between caregiver-child interaction and early childhood development (ECD) has been observed, the underlying biological mechanism remains to be elucidated.

Objective

This study aimed to examine the potential role of epigenome-wide DNA methylation in the association between caregiver-child interaction and ECD among preschool children living in rural China.

Methods

This study was conducted in a rural area in Central China. ECD was evaluated with the Gesell Development Diagnosis Scale (Chinese version), yielding a developmental quotient (DQ), i.e. global neurodevelopmental score (NDS). Caregiver-child interaction was assessed using the Brigance Parent-Child Interaction Scale. Of the 171 children aged 3-6 years who participated in ECD asses

SUBMITTER: Wei M 

PROVIDER: S-EPMC11963332 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature