Construction of ceRNA networks of lncRNA and miRNA associated with intramuscular fat deposition in Ujumqin sheep.

ABSTRACT:

Introduction

The molecular mechanisms underlying intramuscular fat (IMF) deposition are crucial for enhancing lamb meat quality. This process is regulated by a network of transcription factors. Exploring the role of non-coding RNAs, particularly lncRNAs and miRNAs, in IMF deposition can clarify its complex genetics and offer resources for breeding Inner Mongolian local breeds.

Methods

We evaluated carcass and lamb meat quality parameters using 60 six-month-old Ujumqin sheep with similar body weights. To investigate non-coding RNA's role in IMF deposition, we identified differentially expressed genes and pathways between the longissimus dorsi and femoral biceps. Additionally, we analyzed these genes and the lncRNA-miRNA-mRNA co-regulatory network in high- and low-IMF femoral

SUBMITTER: Lan M 

PROVIDER: S-EPMC11963774 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature