Randomized Trials of Renal Denervation for Uncontrolled Hypertension: An Updated Meta-Analysis.

ABSTRACT:

Background

Despite optimal medical therapy, a significant proportion of patients' blood pressure remains uncontrolled. Catheter-based renal denervation (RDN) has been proposed as a potential intervention for uncontrolled hypertension. We conducted an updated meta-analysis to assess the efficacy and safety of RDN in patients with uncontrolled hypertension, with emphasis on the differential effect of RDN in patients on and off antihypertensive medications.

Methods and results

Online databases were searched to identify randomized clinical trials comparing efficacy and safety of RDN versus control in patients with uncontrolled hypertension. Subgroup analyses were conducted for sham-controlled trials and studies that used RDN devices that have gained or are currently seeking US F

SUBMITTER: Mufarrih SH 

PROVIDER: S-EPMC11963938 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature