Grading of Aortic Valve Calcification Severity and Risk Stratification in Aortic Stenosis.

ABSTRACT:

Background

Thresholds of aortic valve calcification (AVC) to define hemodynamically moderate aortic stenosis (AS) from mild are lacking. We aimed to establish a novel grading classification of AVC as quantified by computed tomography and determine its prognostic value.

Methods and results

This study included 915 patients with at least mild AS (mean age 70±12 years, 30% women) from a multicenter prospective registry. All patients underwent Doppler-echocardiography and noncontrast computed tomography within 3 months. Primary end point was the occurrence of all-cause death. Receiver operating characteristic curves analyses were used to determine the sensitivity and specificity of sex-specific thresholds of AVC to identify hemodynamically moderate AS. Optimal thresholds (ie, wit

SUBMITTER: Tastet L 

PROVIDER: S-EPMC11964013 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature