Targeted temperature management at 33 versus 36 degrees after out-of-hospital cardiac arrest: A follow-up study.

ABSTRACT:

Aim

Targeted temperature management (TTM) is commonly used in the setting of out-of-hospital cardiac arrest (OHCA) to improve survival and functional outcomes. However, real-world evidence of effects and optimal temperature are limited. To help address this, we examined associations between TTM and neurologically-intact survival after non-traumatic OHCA across changing institutional TTM temperature goals.

Methods

We performed a single-site, retrospective, cohort study of adults with non-traumatic OHCA who arrived comatose to the emergency department and received TTM from 2010 to 2020. Primary exposure was TTM goal temperature. Institutional goal temperature changed from 33 °C (TTM33-1) to 36 °C (TTM36) in 2014 and back to 33 °C (TTM33-2) in 2017. The primary outcome was neur

SUBMITTER: Doerning R 

PROVIDER: S-EPMC11964768 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature