Prenatal exposure to HIV pre-exposure prophylaxis and birth, growth, and social-emotional developmental outcomes throughout early childhood in Kenya: a prospective cohort study.

ABSTRACT:

Background

As pre-exposure prophylaxis (PrEP) implementation continues to scale up among pregnant people, accruing safety data following prenatal PrEP exposure remains important. In this study, we aimed to evaluate the relationship between prenatal PrEP exposure and birth and infant or child outcomes.

Methods

This prospective cohort study analysed data from the PrEP Implementation for Mothers in Antenatal Care study (NCT03070600). Participants were eligible for inclusion if they were currently pregnant, not currently using PrEP, were aged 15 years or older, planned to remain in the study area, were not enrolled in other studies, and did not have HIV or tuberculosis. Participants enrolled during pregnancy at 20 maternal and child health clinics in western Kenya and were follo

SUBMITTER: Gomez L 

PROVIDER: S-EPMC11964894 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature