Individual-level deviations from normative brain morphology in violence, psychosis, and psychopathy.

ABSTRACT: Neuroimaging research has shown brain morphological abnormalities associated with violence and psychosis, but individual differences are substantial and results not consistent across studies. Normative modeling of brain MRI-features facilitates a systematic mapping of individual brain characteristics of complex phenotypes also in small samples but has not yet been applied to forensic psychiatry populations. We explored brain heterogeneity in persons with a history of severe violence with a comorbid schizophrenia spectrum disorder (SSD-V; n = 38), non-violent persons with schizophrenia spectrum disorders (SSD-NV; n = 138), persons with a history of severe violence without comorbid schizophrenia spectrum disorder (nonSSD-V; n = 20), and healthy non-violent participants (HC; n = 196) from lif

SUBMITTER: Haukvik UK 

PROVIDER: S-EPMC11965457 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature