Markers of Prognosis for Acute Esophageal Necrosis: A Systematic Review.

ABSTRACT:

Introduction

Acute esophageal necrosis (AEN) is a rare and lethal condition that may progress to sepsis and perforations. Most related literature comes from case reports; however, a few small reviews have been published. We conducted a large systematic review of AEN using PubMed, Medline, and Embase to organize data into one consolidated manuscript, find potential prognosticators of illness, and determine possible treatment guidelines for AEN.

Methods

Advanced searches were performed of all English case reports from 1990 to 2021 using medical subject heading terms. Data on patient age, sex, comorbidities, initial presentation, management, progression of illness, and hospital survival were collected.

Results

Our study included 226 articles, encompassing 319 cases. A to

SUBMITTER: Kupferman J 

PROVIDER: S-EPMC11965826 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature