Intravenous Dextrose for the Treatment of Neonatal Hypoglycaemia: A Systematic Review.

ABSTRACT:

Introduction

Hypoglycaemic neonates are usually admitted to neonatal intensive care for intravenous (IV) dextrose infusion if increased feeding and dextrose gel fail to restore normoglycaemia. However, the effectiveness of this intervention is uncertain. This review aimed to assess the evidence for the risks and benefits of IV dextrose for treatment of neonatal hypoglycaemia.

Methods

Four databases and three clinical trial registries were searched from inception to October 5, 2023. Randomised controlled trials (RCTs), non-randomised studies of interventions, cohort studies, and before and after studies were considered for inclusion without language or publication date restrictions. Risk of bias was assessed using Cochrane's Risk of Bias 2 tool or Risk of Bias in Non-Randomiz

SUBMITTER: Roberts LF 

PROVIDER: S-EPMC11965860 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature