Differential cognitive functioning in the digital clock drawing test in AD-MCI and PD-MCI populations.

ABSTRACT:

Background

Mild cognitive impairment (MCI) is common in Alzheimer's disease (AD) and Parkinson's disease (PD), but there are differences in pathogenesis and cognitive performance between Mild cognitive impairment due to Alzheimer's disease (AD-MCI) and Parkinson's disease with Mild cognitive impairment (PD-MCI) populations. Studies have shown that assessments based on the digital clock drawing test (dCDT) can effectively reflect cognitive deficits. Based on this, we proposed the following research hypothesis: there is a difference in cognitive functioning between AD-MCI and PD-MCI populations in the CDT, and the two populations can be effectively distinguished based on this feature.

Methods

To test this hypothesis, we designed the dCDT to extract digital biomarkers that can

SUBMITTER: Wang C 

PROVIDER: S-EPMC11965901 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature