Surgical resection of lymph node positive intrahepatic cholangiocarcinoma may not improve survival.

ABSTRACT:

Background

Nodal positivity is a predictor of poor survival following resection for intrahepatic cholangiocarcinoma (ICC). The aim of this study was to evaluate the impact of surgical resection on survival in patients with lymph node (LN) positive ICC.

Methods

An augmented version of the Surveillance, Epidemiology, and End Results program database was utilized to identify patients with LN-positive ICC without distant metastases from 2000 to 2014. Patients were stratified by treatment: chemotherapy alone or surgical resection with/without chemotherapy. Survival was evaluated using Kaplan-Meier and Cox proportional hazard models.

Results

169 patients who underwent treatment for LN-positive ICC were identified. 88% underwent surgical resection and 12% underwent chemother

SUBMITTER: Kizy S 

PROVIDER: S-EPMC11966089 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature