Early-Life Ozone Exposure and Asthma and Wheeze in Children.

ABSTRACT:

Importance

Ozone (O3) is the most frequently exceeded air pollutant standard in the US. While short-term exposure is associated with acute respiratory health, the epidemiologic evidence linking postnatal O3 exposure to childhood asthma and wheeze is inconsistent and rarely evaluated as a mixture with other air pollutants.

Objectives

To determine associations between ambient O3 and subsequent asthma and wheeze outcomes both independently and in mixture with fine particulate matter and nitrogen dioxide in regions with low annual O3 concentrations.

Design, setting, and participants

This cohort study consisted of a pooled, multisite analysis across 6 US cities using data from the prospective ECHO-PATHWAYS consortium (2007-2023). Included children had complete airway surve

SUBMITTER: Dearborn LC 

PROVIDER: S-EPMC11966328 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature