Psychiatric, Neurological, and Somatic Comorbidities in Intermittent Explosive Disorder.

ABSTRACT:

Importance

Intermittent explosive disorder (IED) is an understudied psychiatric condition marked by impulsive aggression and poorly regulated emotional control, often resulting in interpersonal and societal consequences. Better understanding of comorbidities can improve screening, diagnosis, and treatment.

Objective

To investigate the prevalence of IED and its associations with psychiatric, neurological, and somatic disorders.

Design, setting, and participants

In this cohort study, matched groups of patients with and without IED were identified from the TriNetX Research Network (dated January 31, 2024). Electronic medical record data were analyzed. The mean (SD) time from the first to last known visits was 4.8 (5.4) years.

Exposure

Lifetime diagnosis of IED.

SUBMITTER: Zhang-James Y 

PROVIDER: S-EPMC11966329 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature