Added value of pretreatment CT-based Node-RADS score for predicting survival outcome of locally advanced gastric cancer: compared with clinical N stage.

ABSTRACT:

Objectives

The Node Reporting and Data System (Node-RADS) offers a reliable framework for lymph node assessment, but its prognostic significance remains unexplored. This study aims to investigate the added prognostic value of Node-RADS in patients with locally advanced gastric cancer (LAGC) undergoing neoadjuvant chemotherapy (NAC) followed by gastrectomy.

Materials and methods

This single-center retrospective study included 118 patients with LAGC underwent NAC and gastrectomy. The maximum Node-RADS score and the number of metastatic lymph node stations (defined as LNM-Station) were evaluated on pretreatment CT. The pretreatment Node-RADS-CT and Node-RADS-integrated models were developed using Cox regression to predict overall survival (OS) and disease-free survival (DFS). T

SUBMITTER: Sun Y 

PROVIDER: S-EPMC11966910 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature