Cognitive cerebellum dominates motor cerebellum in functional decline of older adults with mild cognitive impairment.

ABSTRACT:

Objectives

The present study aims to investigate the role that cognitive cerebellar lobules, compared to the motor ones, could have on performance abilities control in older individuals with Mild Cognitive Impairment (MCI).

Methods

Thirty-six participants with MCI were retrospectively recruited from the outpatient clinic for Cognitive Decline and Dementia at Geriatric Clinic and Regional Center for Brain Aging. Cognition was assessed through a reaction time (RT) task in which a mere cognitive (COG) component (RT/S1 COG, RT/S3 COG) has been isolated from a motor (MOT) component (RT/S1 MOT, RT/S3 MOT). Performance abilities were evaluated using Short Physical Performance Battery (SPPB), Tinetti Scale, and Activities of Daily Living (ADL). Finally, structural neuroimaging was c

SUBMITTER: Devita M 

PROVIDER: S-EPMC11967948 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature