Dietary nitrate intake and vegetable consumption, ambient particulate matter, and risk of hypertension in the Nurses' Health study.

ABSTRACT:

Background

Studies have suggested that dietary nitrate could lower blood pressure levels whereas ambient particulate matter (PM) may increase risk of hypertension. However, it is unknown if these exposures may modify each other.

Objectives

We collected information on dietary nitrate intake and vegetables consumption and estimated long-term exposures to ambient PM for women in the Nurses' Health Study.

Methods

Hazard ratios (HRs) and 95% confidence intervals (95% CIs) for risk of hypertension were calculated using Cox proportional hazards models with adjustment for potential demographic, lifestyle and dietary confounders. Interactions were assessed with multiplicative interaction terms and stratified models.

Results

Increases in dietary nitrate intake (per 150 m

SUBMITTER: Li X 

PROVIDER: S-EPMC11968144 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature