Heritability and age-dependent changes in genetic variation of telomere length in a wild house sparrow population.

ABSTRACT: Telomere length (TL) and/or its rate of change are popular biomarkers of senescence, as telomere dynamics are linked with survival and lifespan. However, the evolutionary potential of telomere dynamics has received mixed support in natural populations. To better understand how telomere dynamics evolve, it is necessary to quantify genetic variation in TL and how such variation changes with age. Here, we analyzed 2,083 longitudinal samples from 1,225 individuals across 16 years, collected from a wild, insular house sparrow (Passer domesticus) population with complete life history and genetic relatedness data. Using a series of "animal" models, we confirmed that TL changes with age, reflecting senescence in this population. We found TL to be repeatable (14.0%, 95% CrI: 9.1%-19.9%) and

SUBMITTER: Chik HYJ 

PROVIDER: S-EPMC11968191 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature