Does Levosimendan hasten veno-arterial ECMO weaning? A propensity score matching analysis.

ABSTRACT:

Background

Preliminary evidence from small, single-center studies suggests levosimendan may improve the likelihood of successful venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in patients with cardiogenic shock. However, the literature is limited and presents conflicting results. We aimed to assess the benefits of levosimendan on VA-ECMO for time to successful ECMO weaning, using a pragmatic and rigorous definition of successful VA-ECMO weaning in patients with potential for cardiac function recovery.

Methods

A retrospective bicentric study over 6 years was conducted, including patients who received levosimendan during their ECMO course. Patients with post-cardiotomy cardiogenic shock or end-stage chronic heart failure were excluded. Patients receiving le

SUBMITTER: Paulo N 

PROVIDER: S-EPMC11968594 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature