Evaluating the Implementation of fan-beam CT-guided online adaptive re-planning in definitive cervical cancer radiotherapy.

ABSTRACT:

Background

This study aims to investigate the feasibility of fan-beam computed tomography (FBCT)-guided online adaptive radiotherapy (oART) in radical radiotherapy for cervical cancer.

Methods

Ten patients who underwent radical radiotherapy for cervical cancer were enrolled in this study. All patients received external beam radiation therapy (EBRT) with a prescription dose of 50.4 Gy/28f, and daily oART with FBCT guidance was performed. Dosimetric analysis was conducted on 278 fractions, comparing the adaptive and scheduled plans. The γ passing rate was measured through in-vivo dose monitoring during treatment, using a 3%/3mm gamma criterion with an 88% threshold for alerts. The time invested in the oART workflow was recorded at each step. Acute toxicities were classi

SUBMITTER: Sun S 

PROVIDER: S-EPMC11968674 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature