<i>Uncaria tomentosa</i> extract exerts antimicrobial activity against boar seminal bacteria and influences sperm resilience under different conditions.

ABSTRACT: Uncaria tomentosa (UT) or cat's claw, is a vine belonging to the Rubiaceae family and native to South and Central America. Various parts of the plant, including bark, showed many therapeutic activities (e.g., antioxidant and antibacterial), but the in vitro effects on gametes have still not been investigated. During boar semen storage for artificial insemination purposes, oxidative stress and bacterial contamination negatively affect sperm quality. In this study, we evaluated the tolerance of boar sperm to UT ethanolic extract at four concentrations (1.6 to 0.025 μg/mL). The analyses were carried out on sperm samples under oxidative stress, induced by H₂O₂ and Fe²⁺/Ascorbate, and during 96 h of semen storage at 17°C. The antibacterial activity

SUBMITTER: Scaringi M 

PROVIDER: S-EPMC11968748 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature