Sample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program.

ABSTRACT: Clinical ascertainment and clinical outcome are key features of any large multisite study. In the ProNET and PRESCIENT research networks, the Accelerating Medicines Partnership^® Schizophrenia (AMP^®SCZ) Clinical Ascertainment and Outcome Measures Team aimed to establish a harmonized clinical assessment protocol across these two research networks and to define ascertainment criteria and primary and secondary endpoints. In addition to developing the assessment protocol, the goals of this aspect of the AMP SCZ project were: (1) to implement and monitor clinical training, ascertainment of participants, and clinical assessments; (2) to provide expert clinical input to the Psychosis Risk Evaluation, Data Integration and Computational Technologies: Data Processing, Analysis,

SUBMITTER: Addington J 

PROVIDER: S-EPMC11968923 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature