Pain control following impacted mandibular third molar surgery: a comparison of the effectiveness of two different protocols.

ABSTRACT: The use of multimodal analgesia is a common practice in clinical settings, where a combination of drugs with different mechanisms of action is used to enhance the effectiveness of an analgesic and reduce its adverse effects. This study aimed to compare the efficacy of concurrent ibuprofen and paracetamol with alternate administration in the management of postoperative pain after the surgical removal of impacted mandibular third molars. A single-center, double-masked, parallel-group, randomized controlled clinical trial involved 56 patients undergoing scheduled surgical extraction of impacted mandibular third molars. Patients were randomly assigned to either Group A (Control), where they were instructed to take one tablet of ibuprofen 400 mg and two tablets of paracetamol 500 mg together ev

SUBMITTER: Gaballah K 

PROVIDER: S-EPMC11969014 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature