Hydrogen Oxidation by Bioinspired Models of [FeFe]-Hydrogenase.

ABSTRACT: Synthetic azadithiolate-bridged diiron clusters serve as structural analogues of the active site of [FeFe]-hydrogenases. Recently, an o-alkyl substitution of aniline-based azadithiolate bridge allowed these synthetic models to both oxidize H₂ and reduce H⁺, i.e., bidirectional catalysis. Hydrogen oxidation by synthetic analogues of hydrogenases is rare, and even rarer is the ability of diiron hexacarbonyls to oxidize H₂. A series of synthetic azadithiolate-bridged biomimetic diiron hexacarbonyl complexes are synthesized where the substitution in the para position of the ortho-methyl aniline in the azadithiolate bridge is systematically varied between electron-withdrawing and electron-donating groups to understand factors that control H<

SUBMITTER: Nayek A 

PROVIDER: S-EPMC11969278 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature