Fusing fluorescent proteins and ferritin for protein cage based lighting devices.

ABSTRACT: Ferritin cages are an effective platform to encapsulate and stabilize a range of active cargoes and present a promising stepping stone towards a wide range of applications. They have been explored for optoelectronic applications in combination with fluorescent proteins towards bio-hybrid light-emitting diodes (Bio-HLEDs) only recently. However, protein integration within the cage or coassembled ferritin cages relies on electrostatic interactions and requires the supercharging of the fluorescent protein that easily compromises functionality and stability. To address this limitation, we have developed a fusion protein combining the Thermotoga maritima apoferritin (TmaFt) with a green fluorescent protein named mGreenlantern (mGL). This approach avoids jeopardizing both the cage assembl

SUBMITTER: Sanz-Velasco A 

PROVIDER: S-EPMC11970472 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature