The impacts of air pollution on mortality and hospital readmission among Medicare beneficiaries with Alzheimer's disease and Alzheimer's disease-related dementias: a national retrospective cohort study in the USA.

ABSTRACT:

Background

Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) are prevalent neurodegenerative disorders, posing a critical worldwide public health challenge. Ambient air pollution has been identified as a potential risk factor for AD progression based on toxicological and epidemiological studies. We aimed to evaluate the impacts of air pollution-including fine particulate matter (PM_2·5), nitrogen dioxide (NO₂), summer ozone (O₃), and oxidant-on readmission or death among Medicare enrollees previously hospitalised with an AD/ADRD diagnosis code.

Methods

We constructed a population-based nationwide retrospective cohort including all Medicare fee-for-service beneficiaries (aged ≥65 years) in the contiguous USA (2000-16) hosp

SUBMITTER: Dong S 

PROVIDER: S-EPMC11970897 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature