Unveiling the in vitro activity of extracted Euphorbia trigona via Supercritical Fluid Extraction against pathogenic yeasts, obesity, cancer, and its wound healing properties.

ABSTRACT: Natural products of plant origin are being explored as safe alternatives for illness management. Their extraction processes play a crucial role in determining their phytochemical and pharmacological properties. In this context, Euphorbia trigona was extracted using Supercritical Fluid Extraction with CO₂ (SFE-CO₂) at two operating temperatures: 20 °C and 40 °C. Phytochemical characterization was performed via HPLC, along with anti-yeast evaluation using the well diffusion method, anticancer assessment using the MTT assay, wound healing analysis via the scratch assay, and anti-obesity evaluation through the lipase assay of the E. trigona extract. The results indicated that SFE-CO₂ at 40 °C extracted a greater quantity (0.198 g) of E. trigona than SFE-CO

SUBMITTER: Bazaid AS 

PROVIDER: S-EPMC11971087 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature