3D joint T₁/T₁ _ρ/T₂ mapping and water-fat imaging for contrast-agent free myocardial tissue characterization at 1.5T.

ABSTRACT:

Purpose

To develop a novel, free-breathing, 3D joint T1$$ {T}_1 $$ / T1ρ$$ {T}_{1\rho } $$ / T2$$ {T}_2 $$ mapping sequence with Dixon encoding to provide co-registered 3D T1$$ {T}_1 $$ , T1ρ$$ {T}_{1\rho } $$ , and T2$$ {T}_2 $$ maps and water-fat volumes with isotropic spatial resolution in a single ≈7$$ \approx 7 $$ min scan for comprehensive contrast-agent-free myocardial tissue characterization and simultaneous evaluation of the whole-heart anatomy.

Methods

An interleaving sequence over 5 heartbeats is proposed to provide T1$$ {T}_1 $$ , T1ρ$$ {T}_{1\rho } $$ , and T2$$ {T}_2 $$ encoding, with 3D data acquired with Dixon gradient-echo readout and 2D image navigators to enable 100%$$ 100\% $$ respiratory scan efficiency. Images were reconstructed with a non-rigid motion-

SUBMITTER: Crabb MG 

PROVIDER: S-EPMC11971512 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature