Ontology highlight
ABSTRACT: Background
Neo-left ventricular outflow tract (LVOT) obstruction is a dreaded complication following transcatheter mitral valve replacement (TMVR). Dynamic LVOT obstruction has been reported to cause mechanical intravascular haemolysis due to red cell fragmentation. Intravascular haemolysis can result in a rare but well-described phenomenon in which patients experience dysphagia due to oesophageal spasm. This phenomenon is classically associated with paroxysmal nocturnal haemoglobinuria and has never been reported following TMVR.Case summary
A 77-year-old female presented 8 days following TMVR with presyncope, dyspnoea, and severe dysphagia. Transthoracic echocardiography revealed neo-LVOT obstruction with trivial paravalvular mitral regurgitation. Doppler echocardiography
SUBMITTER: Sargent S
PROVIDER: S-EPMC11971513 | biostudies-literature | 2025 Apr
REPOSITORIES: biostudies-literature