Sex Differences in Embolic Stroke of Undetermined Source: Echocardiographic Features and Clinical Outcomes.

ABSTRACT:

Background

Sex differences in stroke are well-documented, but in embolic stroke of undetermined source (ESUS) remains underexplored. This study aims to investigate sex-related differences in clinical and cardiac features and stroke outcomes in ESUS.

Methods

Retrospective observational single-center study including consecutive ESUS patients. Multivariate regression analyses evaluated the association between sex, echocardiographic features, and 90-day outcomes. Cox regression assessed the independent effect of sex on ischemic stroke recurrence, all-cause death, and atrial fibrillation detection after stroke (AFDAS).

Results

Among 556 patients, 248 (44.6%) were women, who were older and had more severe strokes. Women exhibited larger left atria (LA) as evidenced by a hig

SUBMITTER: Cascio Rizzo A 

PROVIDER: S-EPMC11971535 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature