A specific blend of prebiotics and postbiotics improved the gut microbiome of dogs with soft stools in the in vitro Simulator of the Canine Intestinal Microbial Ecosystem.

ABSTRACT: The Simulator of the Canine Intestinal Microbial Ecosystem (SCIME) allows for the study of the long-term effects of food, supplements, or ingredients on the canine gut microbiome in a simulated proximal and distal colon. This model has been used to evaluate the impact of repeated administration of a test product blend composed of a mixture of baobab fruit pulp, acacia gum, heat-killed Lactobacillus helveticus HA-122, and specific fractions of selected inactivated yeast strains (including Saccharomyces cerevisiae AQP 12260 and AQP 12988 and Cyberlindnera jadinii AQP 12549), on the activity and composition of the gut microbiome of canine donors with soft stools. The SCIME colonic reactors were inoculated with fecal material from 3 different canine donors. After 2 d of stabilization, the 8-d

SUBMITTER: Duysburgh C 

PROVIDER: S-EPMC11971633 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature